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Together, these metabolic alterations suggest a biochemical framework in which inflammation, oxidative stress, and TTR misfolding may be interconnected in TTR-V30M amyloidosis

Disclosures: Zoe Post: Nothing to Disclose, Jonathan Day: Nothing to Disclose, Ashley Cawthon: Nothing to Disclose, Sierra Anderson: Nothing to Disclose, Ana Maria Davila Morales: Nothing to Disclose, Sujit Janardhan: Nothing to Disclose 1708 ESTIMATING THE PREVALENCE OF CHRONIC HEPATITIS B IN THE UNITED STATES BY STATE USING MEDICARE DATA Stephen Congly 1 Mayur Brahmania 1 Conar O'Neil 2 Karen Doucette 2 Mang Ma 2 Carla Coffin 1 , 1 University of Calgary, 2 University of Alberta Background: Current prevalence estimates of patients living with chronic hepatitis B (CHB) in the United States (0.35%) are predominantly based on NHANES survey data which may underestimate at-risk populations

10.1093/pcp/pct201 Plant Cell Physiol