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This is standard refrigerator temperature, not the door shelf where temperature fluctuates every time you open the fridge

Rosa26stop-floxed-YFP mice (RRID:IMSR_JAX:018280

doi: 10.1038/nature13198

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However, someone with decreased intrinsic factor may have symptoms of milder B12 deficiency long before pernicious anemia.[ref] The time to act is long before your body develops full-blown anemia