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However, we have generated a new question: whether SASP factors from aging adipocytes have a similar effect on osteoclasts

Evidence-transparent framing

New Technology Add-On Payment Criteria (1) Newness Criterion Under the first criterion, as reflected in 412.87(b)(2), a specific medical service or technology will no longer be considered new for purposes of new medical service or technology add-on payments after CMS has recalibrated the MS-DRGs, based on available data, to ( reflect the cost of the technology

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To induce this transformation, tumor cells secrete signaling molecules (e.g., Wnt7a [60], and osteopontin [61, 62]), and release exosomes containing miRNAs (e.g., miR-9 [63] or miR-125b [64]) and proteins like survivin [65]