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Adhesion molecules mediating leukocyte migration (from Janeway et al., 1997) Adhesion molecules Ligand on endothelium or expressed on leukocyte extracellular matrix Migration of naive T-cells into lymphoid tissue CD62L (L-selectin) { CD34 { GlyCAM-1 { MadCAM-1 (Mucosae) Migration of memory T-cells into peripheral tissue CD11a/CD18(LFA-1) { CD54 (ICAM-1) { CD102 (ICAM-2) Cutaneous lymphocyte CD62E (E-selectin) antigen (CLA) CD49d/CD29 (VLA-4) CD106 (VCAM-1) CD49d/CD29 (VLA-5) fibronectin Migration of neutrophil and macrophages into peripheral tissue sialyl-Lewis x moiety { CD62E (E-selectin) { CD62P (P-selectin) CD11a/CD18 (LFA-1) { CD54 (ICAM-1) { CD102 (ICAM-2) CD11b/CD18 (MAC-1) CD54 (ICAM-1) pathway of antigen presentation and exposed on the outer cell membrane by Class I molecules