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When opiates are removed, this system rebounds with excessive activity, leading to rapid intestinal contractions and digestive distress

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Honghua Peng, [email protected] These authors have contributed equally to this work This article was submitted to Cancer Immunity and Immunotherapy, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

COST Cost is also a factor to consider