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Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine and trimethylamine-N-oxide, since these metabolites are normally excreted in the urine

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The latest data from the Australian Institute of Health and Welfare estimates 219,000 Australians are living with the illness, she said

A meta-analysis by Sniderman et al

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