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Nedd4-2 is also regulated by 14-3-3 proteins, which recognize phosphorylated motifs adjacent to the WW2 domain in response to hormones, such as aldosterone, insulin or vasopressin 25,26,27,28

doi: 10.1002/1878-0261.12851 57 LegrandAJKonstantinouMGoodeEFMeierP

demonstrated that single nucleotide polymorphisms (SNPs) of the AS3MT gene ought to be considered when determining the therapeutic dose of ATO, and that the urinary primary methylation index (PMI) can be used as a monitoring indicator of ATO-related chronic adverse reactions (AEs) (Zheng et al., 2021)

No detailed data of case group and control group

We thank Andreas Brockmeyer, Jenny Borman and Svenja Heimann for support in mass spectrometry measurements, Christine Nowak for protein and plasmid purification, Sasikala Thavam, Nathalie Bleimling, Jens Warmers and Anna Sophie Sickau for technical support