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Anti-PEG antibodies boosted in humans by SARS-CoV-2 lipid nanoparticle mRNA vaccine

Glossary Abbreviations PASI psoriasis area and severity index BSA body surface area DLQI dermatology life quality index BMI body mass index NMR nuclear magnetic resonance GH growth hormone HDL high-density lipoprotein LDL low-density lipoprotein AST aspartate aminotransferase GT gamma glutamyl transferase HOMA-IR homeostasis model assessment insulin resistance VAT visceral adipose tissue AMFT aortomesenteric fat thickness CPMG CarrPurcellMeiboomGill HMDB Human Metabolome Database MVA multivariate analysis PCA principal component analysis PLS-DA partial least-squares discriminant analysis TSP trimethylsilyl propionic-2,2,3,3- d 4 acid, sodium salt PRICONA PRincipal COmponent Normalization Algorithm ELISA enzyme-linked immunosorbent assay VIP variable influence on projection VAS visual analogue scale FDR false discovery rate PPAR peroxisome proliferator-activated receptor Supporting Information Available The Supporting Information is available free of charge at Figure S1: green line on top showing the accumulated variance explained and blue line underneath showing the variance explained by individual PC

[DOI] [PubMed] [Google Scholar] 30.Broadwell RD, Balin BJ

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

This allows the body to adjust to the supplement