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25-27 Furthermore, IC/BPS patients displaying widespread pain showed multiple indications of central neurobiological pain sensitization, correlating with quantitative sensory testing, fMRI (functional magnetic resonance imaging), and inflammatory markers

This review provides in-depth details of the molecular mechanisms by which paracellular permeability is regulated, with relevance to disease conditions of the gastrointestinal tract

These interactions are still under investigation, and findings are based only on laboratory observations

They vary from two to around 50 amino acids, after which they are commonly referred to as proteins

This involves taking smaller doses over a few weeks or months before stopping completely