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the liver) show that ceramide accumulation or depletion is sufficient to regulate Srebf1 gene expression, as well as sterol response element (SRE)-mediated transcriptional targets (71, 72)

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Huang, KL, Mashl, RJ, Wu, Y, Ritter, DI, Wang, J, Oh, C, Paczkowska, M, Kim, T, Logothetis, CJ, Wistuba, II, Chen, K, Liu, Y, Akbani, R, Broom, BM, Ju, Z, Kanchi, RS, Korkut, A, Li, J, Liang, H, Ling, S, Liu, W, Lu, Y, Mills, GB, Uppore Kukkillaya, AR, Weinstein, JN, Zhang, J, Liu, X, Wang, L , Fregnani, JG, Reis, RV, Ajani, JA, Behrens, MC, Bondaruk, J, Broaddus, R, Czerniak, BA, Esmaeli, B, Fujimoto, J, Gershenwald, JE, Guo, CC, Lazar, A, Moran, C, Ramondetta, LM, Rice, DC, Sood, AK, Tamboli, P, Thompson, T, Troncoso, P, Tsao, A, von Deimling, A, Meric-Bernstam, F