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High Dose Vitamin B12 Side Effects (What They Can Look Like) Reported high dose vitamin B12 side effects are generally mild and non-specific

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For this reason, there is no established Tolerable Upper Intake Level (UL), meaning there's no known toxic dose for healthy individuals

The compounding industry argued, not unreasonably, that the restrictions had driven patients toward unregulated gray-market sources: overseas chemical suppliers operating under "research use only" labels with no quality controls, no dosage verification, and no pharmaceutical oversight