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The researchers demonstrated that erythrocytes production is aberrant in alas2-oralad defective embryos using a zebrafish model

The expressions of ROCK, MLCK, and MYPT1 are used to assess the ROCK/MLCK/myosin pathway, which is responsible for bile canaliculi (BC) spontaneous contractions and dilations, which are essential for bile acid (BA) efflux [52]