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Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity

Consistent treatment over time can soften lines progressively, as muscles that are regularly relaxed gradually thin and the associated lines become less deeply etched

Nagayama H, Hamamoto M, Ueda M et al (2004) The effect of ascorbic acid on the pharmacokinetics of levodopa in elderly patients with Parkinson disease

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It is suggested that the synergistic effects of the Ac-G combined treatments in CAA result from their impact on protecting the SOD enzyme and reducing the oxidative stress-induced depletion in cellular GSH levels, where the two Ac-G combination ratios of 8:1 and 4:1 [(1 + 0.125) and (1 + 0.25) g/mL] were significantly more effective in preserving the SOD enzyme activity and reducing GSH depletion when compared to the corresponding gingerol treatments