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4.55.5 mm per 100 mg, 911 mm % 200 mg and 1316 mm per 300 mg charcoal etc., Lane 1- Lung microsomes of normal guinea pigs Lane 2- Lung microsomes of guinea pigs exposed to smoke from cigarettes without charcoal filter Lane 3- Lung microsomes of guinea exposed to smoke from cigarettes equipped with activated charcoal filter containing a mixture of 0.1 g of BS 52/60 and 0.1 g of BS 60/72 Table 1

Supporting the relevance of these findings, long-term exposure to e-cigarette aerosols consistently 42 leads to a decrease in the expression of DNA repair genes ( ERCC1 , XPC , OGG1 , ATM ) in vitro 36 , in mice 43 , and in e-cigarette users 68

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