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Meanwhile, hypoxia results in excessive production of intracellular reactive oxygen species (ROS), which in turn cause oxidative injury in tissues [7], endoplasmic reticulum (ER) stress [8], autophagy and apoptosis [9]

2024 Nov 15;24(6):214

Prognostic significance of the programmed death ligand 1 expression in clear cell renal cell carcinoma and correlation with the tumor microenvironment and hypoxia-inducible factor expression

The human skin is not only an estrogen target but also a primary estrogen source

CdCl 2 did not affect the mitochondrial proteins NDUFA9 and ATP5A, suggesting that decreased mitochondrial content is not the main cause of decreased mitoSTAT3 levels in vivo (Fig