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Rough endoplasmic reticulum as indicated by purple arrows

The lowest-observed-adverse-effect level (LOAEL) reported in this study was 10 mg/kg body weight, showing a slight, but significant increase in sorbitol dehydrogenase (SDH) activity and mild hepatic centrilobular vacuolization

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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Andrikopoulos K, Liu X, Keene D, Jaenisch R, Ramirez F

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