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Unaugmented Gpx/GR Ratio In previous simulations, the standard model involved a higher concentration of Gpx (2 M) than that of GR (0.05 M), following from our proposed order of genes in the plasmid

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The regulatory role of mitochondria in ferroptosis shown in Figure 5

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The specialist enzymatic antioxidant families include those that target hydrogen peroxide (H 2 O 2 ), which is the major redox signalling ROS reviewed by 5,24,25 , and those that target superoxide anion radical (O 2 - ) for the generation of H 2 O 2 as a product[reviewed by 26,27