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It has an excellent safety profile, which is why higher doses like 1000 mcg are common and well-tolerated

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RGCs isolated from retinas 24 h after IR show that the signaling cascades regulating ferrous iron (Fe 2+ ) metabolism, such as TNFRSF1A and FAS, undergo significant changes, which causes retinal damage after I/R (Dvoriantchikova et al., 2023)

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2023;15 doi: 10.1080/19490976.2023.2208503

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