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Lipinska et al., 2025), EVs have been applied using heterogeneous experimental protocols, with doses generally ranging from low g/mL concentrations (310 g/mL) to higher fixed doses around 120200 g/mL, and exposure times spanning from short co-culture periods of a few hours (up to 14 h) to prolonged treatments covering complete in vitro maturation windows according to the specie (approximately 1838 h)

Nat Prod Commun 9(4):1934578X1400900434 Pasupuleti VR, Sammugam L, Ramesh N, Gan SH (2017) Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits

Lysophosphatidic acid receptor 5 contributes to imiquimod-induced psoriasis-like lesions through NLRP3 inflammasome activation in macrophages

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