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Blood 124:3474 van de Donk NW, Janmaat ML, Mutis T, Lammerts van Bueren JJ, Ahmadi T, Sasser AK et al (2016) Monoclonal antibodies targeting CD38 in hematological malignancies and beyond

These patients were randomly assigned to receive either 15mg/week of oral MTX (2 tablets of 7.5mg each plus a dummy prefilled syringe

For all these reasons, neuroprotective strategies that specifically target neurons alone may be insufficient to improve neurological outcome after ischemic stroke

Verify authorization requirements before administering the drug, not after the claim comes back denied

Understanding these differences helps set realistic expectations and supports smarter skincare decisions