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Resveratrol alleviates chronic real-world ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice

This is the first time a GLP-1 receptor agonist has moved beyond weight management and diabetes treatment

RIPK3 RIPK3 inhibitor GSK-872 suppresses RIPK3 expression, mitigates hepatocyte necroptosis, and modulates the Nrf2/NFB signaling axis to improve oxidative stress and inflammatory phenotypes [137]

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These low-toxicity interventions do not replace surgery, cytotoxics, or targeted drugs, but when matched to tumor genotype and patient metabolic state, they can widen the therapeutic window of virtually every modern anti-cancer modality 1,387,398,399