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No significant difference in food intake was observed between treated and control mice in related studies, indicating that its antiobesity effect mainly depends on regulating fat metabolism rather than suppressing appetite - a unique advantage in obesity research

In severe cases, the body may struggle to absorb enough of the vitamin from oral sources leading to continued symptoms of deficiency

The 250500 mcg subcutaneous range used in current research contexts sits below the 1 mg clinical trial dose, partly because subcutaneous bioavailability differs from the oral administration used in some trial arms

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