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gut microbiota metabolism of l-carnitine and cardiovascular risk

gut microbiota metabolism of l-carnitine and cardiovascular risk γ-Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in Gut‐Heart Axis: Metabolites

Microbiota in GutHeart Axis: Metabolites and Mechanisms in Cardiovascular Disease PMC Role of gut microbiota and derived metabolites in cardiovascular diseases ScienceDirect Linking anaerobic gut bacteria and cardiovascular disease Nature Microbiology Recent advances in modulation of cardiovascular diseases by the gut microbiota Journal of Human Hypertension Frontiers Gut macrobiotic and its metabolic pathways modulate cardiovascular disease

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[DOI] [PMC free article] [PubMed] [Google Scholar] (90).Soerianto W

gut microbiota metabolism of l-carnitine and cardiovascular risk -Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in GutHeart Axis: Metabolites

For example, deletion or pharmacological inhibition of NAMPT promotes a very sharp decline in muscle, but a more modest reduction in the liver [37,38,84]

gut microbiota metabolism of l-carnitine and cardiovascular risk -Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in GutHeart Axis: Metabolites

Among various mediators, transforming growth factor- (TGF-) and MAPK pathways are key effectors that integrate redox signaling with fibrogenic gene expression

gut microbiota metabolism of l-carnitine and cardiovascular risk -Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in GutHeart Axis: Metabolites

This can help reduce fatigue, improve cognitive performance, and alleviate muscle soreness

gut microbiota metabolism of l-carnitine and cardiovascular risk -Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in GutHeart Axis: Metabolites

It can be an appropriate response (exercise, fever, anxiety) or inappropriate (overactive thyroid, certain medications, dehydration)

gut microbiota metabolism of l-carnitine and cardiovascular risk -Butyrobetaine Is a Proatherogenic Intermediate in Microbial to TMAO: Cell Metabolism Microbiota in GutHeart Axis: Metabolites
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