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The negatively charged residues in the p53 TAD PEP were not crucial for FOXO4 FHD binding (Table 1)

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The researchers commented that DSIP exerts stimulating influence upon the superoxid-dismutese, catalase, ceruloplasmin activities as well as the level of nonenzymatic antioxidants--urea and uric acids, because during organism aging the antioxidant defense systems are being suppressed