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IGFBP-2 is a major binding protein for IGF-2, crucial for regulating IGF-2 availability in the brain [106, 107]

Two key Buffalo Bills free agent signings suspended for violating NFL PED policy Defensive lineman Michael Hoecht and defensive tackle Larry Ogunjobi were each banned six games for violating the NFL Performance Enhancing Drug policy, Bills general manager Brandon Beane said at a press conference Friday