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Under different pathophysiologic conditions, activated macrophages are capable of differentiating into phenotypically different states, including the classically activated (M1) and the alternatively activated (M2) macrophages

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4.3 Membrane perturbation Lipophilic organosulfur compounds (OSCs), including S-methyl-L-cysteine derivatives and long-chain thioethers, insert into bacterial membranes, increasing fluidity and disrupting bilayer integrity, proton gradients, and ATP synthesis (Shin et al., 2024

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