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The careful selection of ligation sites Val25-Thr26 and Glu49-Ser50 helped maintain the hydrophobic balance and preserve biological activity

S.SpeerO.et al (2014)

Blood 113 , 32763286 (2009)

Moreover, subsequent research should investigate the prospective contributions of these interventions beyond sarcopenia, particularly in the realms of preventing or alleviating age-related vascular aging, metabolic syndrome, and frailty

They increase LRRK2 activity, which impairs alpha-synuclein breakdown in neurons and may indirectly affect PD development (Streubel-Gallasch et al., 2021)