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It does this by interfering with the SNARE protein complex, a crucial component in the process that allows nerve signals to tell muscles to contract

The modifying effect of Xmn1-HBG2 on thalassemic phenotype is associated with its linked elements in the beta globin locus control region, including the palindromic site at 5HS4

And, so far, that threshold has not been achieved to the satisfaction of the Saudis

An imbalance in these components can cause bile to become supersaturated with cholesterol, which contributes to gallstone formation

Antibodies used in this study include YFP antibody for YFP-BubR1 detection (homemade in JN lab 48 , 1:2000), Cdc20 (Santa Cruz, sc-13162, 1:1000), Mad2 (Bethyl, A300-301A, 1:1000), Apc7 (Santa Cruz, sc- 365649, 1:1000), Apc4 (Santa Cruz, sc-514895, 1:1000)