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For example, MMP-9, produced by both AECs and Thy-1-negative fibroblasts, not only activates TGF- to sustain a profibrotic cycle but also enhances fibroblast migration and collagen deposition ( + /collagen + bone marrow-derived cellsexploit the proteolytic activity of MMP-2, MMP-8, and MMP-9 to degrade ECM barriers, facilitating their migration into lung tissue and subsequent differentiation into myofibroblasts ( However, paradoxically, certain MMPs demonstrate context-dependent antifibrotic potential, suggesting protective roles under specific conditions

A randomized intervention study to evaluatethe effect of calcitriol therapy on the renin-angiotensin system in diabetes

We also review therapeutic approaches for enhancing GSH status

Although KD significantly limits carbohydrate intake, it maintains the minimum carbohydrate supply necessary for gluconeogenesis (48)