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For PDX tumors, frozen sections were established and stained with 10 M DCFH-DA and 20 M BODIPY 581/591 C11 for 30 min, and then washed twice by PBS

Taken together, our study demonstrated that ferroptosis played an important role in AKI induced by FA overdose injection in mice, which could be alleviated by LA supplementation, indicating that LA may be used as a potential therapeutic approach to ameliorate AKI caused by drugs or toxicants in the clinic

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Glutathione is a tripeptide, made from three amino acids: Glutamate (glutamic acid) Cysteine (the rate-limiting building block) Glycine Together, these form a molecule your cells use to: Neutralize free radicals Detoxify heavy metals and pollutants Regenerate other antioxidants like vitamin C and E Maintain mitochondrial function Support immune and liver health Your body produces glutathione constantly but it needs the right raw materials and metabolic support to keep up

Theranostics 11(18):88138835