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A pooled quality control (QC) sample prepared by mixing equal aliquots of all plasma samples was analyzed in parallel and injected at regular intervals (every five samples) to assess analytical stability

The cells treated with Sp showed slight enhancement in levels of GSH (~1.2 fold), together with minor alterations in GSSG levels, compared to untreated samples which exhibited higher GSSG content, thus indicating efficient recycling of GSSG to GSH (Fig

Reported activators of GPX4, such as 1d4, SeMet, and CDDO, or inhibitors of GPX4 degradation are promising for pain relief, which may be related to the inhibition of inflammation and oxidative stress

Accordingly, Bors et al

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