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Am J Clin Dermatol 22(1):5565

Sickle-cell disease

10.1016/j.molcel.2017.05.028 2 BylerD

Besides targeting ERK pathway, other cardioprotective natural products such as butin, xanthohumol, botulin, fisetin, paeonol and danshensu combination (PDSS), punicalagin and 3-caffeoyl, 4-dihydrocaffeoyl quinic acid can activate Nrf2 through phosphorylation AMPK, GSK3, p38 MAPK, and PI3K/AKT