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The peptide appears to act through direct interaction with adipocytes (fat cells), potentially involving activation of hormone-sensitive lipase (HSL) and modulation of -adrenergic receptor signaling pathways

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doi: 10.1016/S0021-9258(19)50898-5 37 ByardJL

A narrative review concluded that the practice is controversial because there are no standardized dosing protocols and nearly onethird of patients report adverse effects, ranging from mild gastrointestinal symptoms to liver dysfunction and lifethreatening allergic reactions