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500 However, there is currently no evidence indicating that tumor stem-like cells or certain drug-resistant cells with enhanced mitochondrial respiration exhibit elevated levels of lipoylated enzymes

This increased period of receptor agonization is responsible for a hyperexcitation of the cholinergic nervous system leading to individual changes and finally death

Quality filtered reads were mapped on assembled contigs to obtain abundance profiles, which were normalized to CPM (Counts Per Million) using EdgeR v3.10.2 35

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The protein was concentrated to ~ 12 mg ml 1 in 25 mM tris (pH 8.0), 250 mM NaCl, and 2 mM tris(2-carboxyethyl) phosphate (TCEP) and stored in aliquots at 80 C