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Nothing wrong, that is, other than regular old human aging, which is not part of Aspreys plan

Even without knowing if you are "salt sensitive," certain subgroups of the population are more responsive to reduced sodium intake: Those with hypertension Older individuals African Americans For references and more information , see the section on hypertension in the Sodium article

Uddin MH, Rumman M, Sarowar T

Production requires a considerable metabolic input from ATP, methyl groups, and specific nutrients, including B vitamins, selenium, and amino acids

The glutathionuria is due to their inability to break down the GSH that is both filtered and secreted in renal tubular fluid