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A5 metallothioneins (MTs) and the brain MTs can act as Zn acceptors and donors inside the cell, exchanging metal ions with proteins

These studies indicate that overproduction of glutathione drives the survival and growth of a small subset of lymphoid tumor cells in 3D gels and xenografts, likely TIC or TIC-like cells, and that glutathione is selectively required for tumor growth in females of a mouse model of lymphoma

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Acute renal failure is, a dose limiting adverse effect, considered one of most common toxicity that complicates the treatment with ciprofloxacin

Physiol Rev 74:139162