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Further studies generated pharmacokinetic profiles of intranasal vascular endothelial growth factor in rats and intranasal allopregnanolone in mice, which measured the highest drug concentrations in the trigeminal nerve, optic nerve and olfactory bulb followed by the cerebrum and hippocampus [79, 80]

Among these disorders, goiter is commonly observed in the general population and can be presented as either diffuse or nodular types based on thyroid histology

Human CBS is a complex multidomain enzyme that requires PLP for its activity and binds to a heme group that serves a regulatory role in its enzyme activity

GSH and pyroptosis Pyroptosis is a form of lytic cell death characterized by gasdermin-mediated plasma membrane pore formation, leading to osmotic swelling, membrane rupture, and the release of mature pro-inflammatory cytokines, including interleukin 1 beta (IL1B, also known as IL-1) and interleukin 18 (IL18)

Neurochemical Research 27, 389-394CrossRefGoogle ScholarPubMed 106Bolaos, J.P., Heales, S.J., Peuchen, S