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Adult dogs dosed intramuscularly for three treatments at 12.5 mg/kg followed by 57 oral treatments at 12.5 mg/kg all at 12 hour intervals did not exhibit either significant clinical signs or effects upon the clinical chemistry hematological or histological parameters

We indicated in the CY 2026 OPPS/ASC proposed rule, we believed hospitals would incur an initial one-time cost to update their processes and systems to (1) identify and collect the newly proposed data elements, and (2) encode the standard charge information for the newly proposed data elements in the CMS standard template

We assigned our proposed rates for these services based on our evaluation of the resources needed to perform these services

reported that treatment with daratumumab increases MM cell death, especially in the presence of a subset of CD14 + /CD16 + monocytes, and that combining daratumumab with anti-CD47 enhances the elimination of MM cells that are resistant to daratumumab alone (66)