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doi: 10.1016/S0891-5849(01)00480-4

Therefore, therapies targeting only cartilage or synovium may be insufficient

Nat Rev Neurosci 12:88104 Barbeito LH, Pehar M, Cassina P et al (2004) A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

It could mean that a FODMAPs diet works because IBS is related to histamine intolerance or it could mean that the people diagnosed with IBS were really dealing with gut-related histamine symptoms.[ref] Additionally, the low FODMAPs diet may help to decrease intestinal barrier permeability