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A more recent randomized, double-blind, placebo-controlled study in 30 patients with type 2 diabetes found that intravenous infusion of 600 mg of lipoic acid improved the response to the endothelium-dependent vasodilator acetylcholine but not to the endothelium-independent vasodilator, glycerol trinitrate (63)

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It helps protect kidney cells from oxidative damage caused by reactive oxygen species (ROS) and toxins, particularly in conditions like acute kidney injury (AKI) and chronic kidney disease (CKD)

Accumulating evidence suggests that chemical constituents of black cumin seeds are chemopreventive and potent in inhibiting cell proliferation and provoking apoptosis (Table 2)

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