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RBCs also contain a large network of antioxidant proteins that can react and deactivate oxidant species very rapidly, preventing the damage of protein and lipids essential for RBC function

Targeting mitochondria in therapy: toxicity, mechanistic ambiguities, and translational barriers Although mitochondrial-targeted therapies have shown great potential in various cancers, they still face significant challenges in clinical advancement

Each one of those functions requires the molecule to remain in its reduced state