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Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits

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Among the main inflammatory mediators, CRP plays a crucial role in atherogenesis by promoting complement activation, enhancing macrophage lipid uptake, stimulating pro-inflammatory cytokine release, inducing monocyte tissue factor expression, impairing endothelial function, and inhibiting nitric oxide production, further aggravating vascular injury (Shrivastava et al

M., Parr, T., & Murton, A