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Toronto, ON: John Wiley & Sons Canada, Ltd

Nimmagadda, VK

The formation of reactive sulfamethoxazole metabolites locally results in dendritic cell maturation, the provision of antigens (drug-protein adducts) for T-cell activation and stress signaling when generated in excess [143, 150,151,152]

They are pharmacologically active compounds studied for neurological conditions, cognitive performance, and anxiety regulation

As a metabolic hub, glutamate is crucial for the biosynthesis of non-essential amino acids, including proline, aspartate, alanine, and serine, which serve as precursors for cysteine, glycine, asparagine, and arginine