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Description

In intestinal epithelial cells, this enhanced contractile tension induces centripetal contraction of the perijunctional actomyosin ring, leading to internalization and reorganization of junctional proteins, including claudins, occludin, ZO-1, and adherens junction components, resulting in reversible TJ opening and increased paracellular permeability

Journal of Applied Physiology

(2018) 13:e0196716

doi: 10.1016/0304-4165(77)90152-0

At the signaling pathway level, chromium impedes kinase cascades that impair insulin signaling, consequently improving insulin sensitivity in peripheral tissues