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Building off the wealth of literature and clinical practice that uses certain organ-specific plasma proteins to noninvasively assess aspects of organ health, such as alanine transaminase for liver damage, we hypothesized that comprehensive quantification of organ-specific proteins in plasma could enable minimally invasive assessment and tracking of human aging for any organ

doi: 10.1016/j.kint.2022.05.012 129 AlaeeMAkbariAKaramiHSalemiZAmriJPanahiM

Integration: Optimize diabetes control first (6-12 months achieving target HbA1c)

Thus, the effects of drug administration on MnPN and VLPO neurons may have resulted in changes in sleep-wake amount

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