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Importantly, a balanced gut microbiota supports the production of anti-inflammatory cytokines, such as IL-10, which help protect both the intestinal barrier and the BBB (Mou et al., 2022)

J Biol Chem 294:48434853 Tanaka Y, Gleason CE, Tran PO, Harmon JS, Robertson RP (1999) Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants