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On the basis of impaired cushioning function, especially of large arteries, arterial stiffness causes (i) ISH, (ii) reduced coronary perfusion and increased afterload with resulting left ventricular diastolic dysfunction, and (iii) microvascular alterations with resulting end-organ damage (e.g., HFpEF, vascular dementia, and chronic kidney disease)

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Control the Pace of Drinking : Limiting intake to one standard drink per hour gives the liver time to metabolize alcohol safely

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Therapeutic Drug Monitoring