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In vivo and ex vivo imaging of brain-targeted properties Although the BBB is essential for maintaining the proper function of the CNS, it also poses significant challenges for treating neurological disorders, such as AD [68]

FIGURE 1 3 Plant localization and pharmacokinetics of saponin compounds The saponin components of PT are predominantly found in the roots, with the concentration in the aboveground parts amounting to only about one-fifth to one-quarter of that in the roots, which is the primary rationale for utilizing the roots for extraction and medicinal purposes (Park et al., 2008

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Spiller HA, Winter ML, Klein-Schwartz W, et al