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Intestinal permeability in spondyloarthritis and rheumatoid arthritis: a systematic review of the literature

Glycolysis converts the 13 C-glucose tracer to M3-pyruvate isotopologues which are oxidized to M2-acetyl-CoA by PDC and finally condensed with oxaloacetate to M2-citrate

In the mouse brain, the activity of the pathway is lower as compared to the liver, but the flux can be increased by oxidative stress (Vitvitsky et al., 2006