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Additionally, Alexa Fluor 555 donkey anti-mouse IgG (H + L) (1:200, A31570, Invitrogen) was used to visualize CD45 expression

Brain 122:22792295 Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (2000) Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

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Alterations in autophagic cycle rate (flux), which initiates with formation of phagophore and terminates with degradation of autophagosome cargo after its fusion with lysosome, are generally observed in response to stress [6]